This image demonstrates the blend of mathematics and art during the Renaissance and demonstrates Leonardo's deep understanding of proportion. In addition, this picture represents a cornerstone of Leonardo's attempts to relate man to nature. Encyclopædia Britannica online states, "Leonardo envisaged the great picture chart of the human body he had produced through his anatomical drawings and Vitruvian Man as a cosmografia del minor mondo (cosmography of the microcosm). He believed the workings of the human body to be an analogy for the workings of the universe."
The title of the painting, which is known in English as Mona Lisa, comes from a description by Renaissance art historian Giorgio Vasari, who wrote "Leonardo undertook to paint, for Francesco del Giocondo, the portrait of Mona Lisa, his wife."